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 Used for building muscle
glycobol works, not like typical muscle gainers, but primarily by its ability to mimic and boost insulin.* on its own, insulin is a powerful growth peptide, but it also plays a critical role in the action of androgens. just like insulin, androgens are another fundamental class of endocrine hormones. studies suggest that androgens fail to sustain a positive muscle nitrogen balance in the absence of insulin, emphasizing the critical role of insulin as a potential limiting factor to the anabolic capacity of androgens. therefore, glycobol may be used to optimize and exaggerate gains by its essential synergistic contribution.*
insulin also interacts synergistically with gh, igf and thyroid hormones to compound growth effects, even when these endocrine co-factors are only present at average physiological levels. therefore, glycobol can be used to support impressive natural muscle gains and body recomposition as an effective stand-alone agent too.*
glycobol:
promotes muscle mass, strength and endurance.*
encourages fat loss.*
improves recovery time by rapid glycogen resynthesis.*
provides lasting "pump", hardness and vascularity.*
drives amino acid and creatine uptake into muscle.*
promotes muscle protein synthesis and reduces breakdown.*
optimizes nutrient utilization.*
you asked for something innovative, now you've got it!
glycobol blend:
sodium r-lipoate (na-r-ala)
ala is naturally produced in the body as a mitochondrial enzyme cofactor. it is important to aerobic metabolism. ala has been suggested to increase cellular uptake of glucose to cell membranes by recruiting the glucose transporter glut4.* ala improves skeletal muscle glucose transport, resulting in desirable blood glucose disposal and increased muscle glycogen concentrations.* (1) studies also suggest that in muscle, ala is a potent anti-oxidant which protects cells from oxidative stress-induced insulin resistance.* (2) the ala used in this formula is chemically stabilized and of high quality.* it's one of the most active isomers and one of the highest efficiency salts commercially available.* ala is an invaluable addition that offers a multitude of benefits plus countless extras for any serious athlete.*
bottom line: best way to describe this effect is that it almost adds a filter to the muscle fibers; taking in what it needs to prepare for growth.*
trigonella seed isolate (standardized to 10% 4-hydroxyisoleucine)
fenugreek has been successfully applied for thousands of years to support health.* modern research suggests that it supports endurance and lowers blood lactate concentrations dramatically.* use of fenugreek seed may also help decrease fat accumulation.* these results suggest that this improvement in endurance and reduction in body fat is caused by an increase in the utilization of fatty acids as an energy source.* (3) fenugreek supplements high in 4-hil have also been suggested to increase post-exercise glycogen resynthesis in athletes, which promotes rapid recovery and helps reduce training fatigue.* (4) the visible results of this glycogenic effect are big, pumped muscles that look extremely full and vascular.*
bottom line: helps you use fatty acids as an energy source, rather than store them as fat!*
phellodendron extract (standardized to 90% berberine)
phellodendron is one of the highly valued traditional chinese herbs. it is reported that some subjects show improved strength in response to phellodendron isolates.* laboratory studies suggest that one of these alkaloidal isolates called berberine may accomplish these benefits by promoting insulin production.* (5) improved health and increased physical performance encourages greater strength and muscle gains in the gym.*
bottom line: increased performance encourages greater strength and muscle gains.*
cinnamon bark 20:1 extract (standardized for 16% flavonoids)
cinnamon is a common spice used all over the world, but it's not commonly known that the spice has significant health supportive value.* cinnamon contains the element chromium, which is needed for proper glucose metabolism, and also compounds called flavonoids. flavonoids are potent anti-oxidants. the specific flavonoids found in cinnamon bark suggest to stimulate glucose uptake and glycogen synthesis similar to insulin.* these flavonoids may activate receptors by direct insulin mimicking action, or indirect insulin potentiation, or both.* (7) if you train consistently and have a healthy diet, your big muscular improvements from this powerful little cinnamon extract might surprise you.*
bottom line: insulin is very anabolic, so the insulin boosting action of cinnamon extract can encourage bigger, stronger muscles.*
bis(maltolato)oxovanadium (bmov)
bmov is an organic form of the mineral vanadium. although elemental vanadium and inorganic salts of vanadium show significant biological potential, it has a poor health supportive index due to low gastrointestinal absorbance.* bmov is recognized as safer, more absorbable, and able to deliver a health supportive effect up to 50% greater than the inorganic forms.* (9) vanadium is one of the rare microelements that can promote a profound boost in endurance and strongly support anabolism.* bmov can promote muscle hardness.* the form of vanadium used in this formula is one of the very best you can find, if not the best.*
*bottom line: promote muscle hardness and vascularity!*
references
(1) the antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both glut4 translocation and glut4 activation: potential role of p38 mitogen-activated protein kinase in glut4 activation.; konrad d, somwar r, sweeney g, yaworsky k, hayashi m, ramlal t, klip a.; diabetes. 2001 jun;50(6):1464-71.
(2) protection against oxidative stress-induced insulin resistance in rat l6 muscle cells by mircomolar concentrations of alpha-lipoic acid.; maddux ba, see w, lawrence jc jr, goldfine al, goldfine id, evans jl.; diabetes. 2001 feb;50(2):404-10.
(3) effects of fenugreek seeds (trigonella foenum greaecum) extract on endurance capacity in mice.; mayumi ikeuchi, et al; journal of nutritional science and vitaminology; vol. 52 (2006), no.4 pp.287-292.
(4) the addition of fenugreek extract (trigonella foenum-graecum) to glucose feeding increases muscle glycogen resynthesis after exercise.; ruby bc, gaskill se, slivka d, harger sg.; amino acids. 2005 feb;28(1):71-6.
(5) therapeutic effect of berberine on 60 patients with non-insulin dependent diabetes mellitus and experimental research; ni yanxia, et al.; chinese journal of integrated traditional and western medicine 1995; 1(2); 91-95.
(6) berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins; kong weijia, et al.; nature medicine 2004; 10(12): 1344-1351.
(7) isolation and characterization of polyphenol type-a polymers from cinnamon with insulin-like biological activity.; anderson ra, broadhurst cl, polansky mm, schmidt wf, khan a, flanagan vp, schoene nw, graves dj.; j agric food chem. 2004 jan 14;52(1):65-70.
(8) cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3t3-l1 adipocytes.; cao h, polansky mm, anderson ra.; arch biochem biophys. 2007 mar 15;459(2):214-22. epub 2007 jan 25.
(9) trace elements in nutrition.; dreosti ie.; med j aust., 1980 august 9;2(3):117-23.
ingredients:
120 capsules
serving size:1capsule
servings per container:120
2 servings provide:
na-r-ala 250mg
glycobol complexe 750mg
trigonella seed isolate (standardized to 10% 4-hydroxyisoleucine), phellodendron extract (standardized to 90% berberine), cinnamon bark 20:1 extract (standardized for 16% flavonoids), bmov (bis-malto-oxovanadium)
other ingredients
gelatin, cellulose
directions for glycobol: to assess tolerance take 1 capsule with a meal containing 50-100 grams of complex carbohydrates. the next day use as follows.
when bulking: take 2 capsules with a meal containing at least 50-100 grams of complex carbohydrates in the am and again in the pm.
when dieting: take 2 capsules 30 minutes before a meal containing at least 25-50 grams of complex carbohydrates in the am and again in the pm.
do not exceed 4 capsules per day.
on workout days take 2 capsules with pre-workout meal.
warnings: you should not take this product if you have any prior medical condition including diabetes. consult your doctor before using this product. keep out of reach of children.
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